Gomez began her acting career on the childrens television series Barney & Friends (2002–2004). As a teenager, she rose to prominence for starring as Alex Russo on the Disney Channel television series Wizards of Waverly Place (2007–2012). Alongside her television career, Gomez appeared in the films Another Cinderella Story (2008), Wizards of Waverly Place: The Movie (2009), Ramona and Beezus (2010), Monte Carlo (2011), Spring Breakers (2012), Neighbors 2: Sorority Rising (2016), and The Dead Dont Die (2019), and voiced Mavis in the Hotel Transylvania film franchise (2012–2022).

Gomez executive produced the Netflix television series 13 Reasons Why (2017–2020) and Living Undocumented (2019) through her production company, July Moon Productions. Additionally, she executive pro...